Efficacy of Lifestyle Interventions on Body Weight and Elevated Liver Enzymes among Patients with Non-Alcoholic Fatty-Liver Disease

Document Type : Original Article

Authors

1 Medical surgical Nursing Faculty of Nursing- Menoufia University Egypt

2 community health nursing faculty of nursing-Menoufia university- Egypt

3 community health nursing faculty of nursing Menoufia University-Egypt

4 Lecturer of Community health nursing, Faculty of Nursing/ Menoufia University, Egypt

Abstract

Non-alcoholic fatty-liver disease is called the silent epidemic mortality for young adults. Lifestyle interventions including healthy dietary, physical activity and exercise program remain the cornerstone treatment approach for this disease. Aim: To examine the effect of lifestyle interventions on bodyweight and elevated liver-enzymes among patients with non-alcoholic fatty-liver disease. Methods: Design: A qausi-experimental design. Subjects: A simple random sample of 200 patients with non-alcoholic fatty-liver. Sitting: Outpatients' clinics of Teaching Hospital and the National Liver Institute, Menoufia Governorate, Egypt. Instruments: Five tools: Structured Interview questionnaire, Reported patient's dietary practices questionnaire, The Nordic Physical Activity and Exercise questionnaire-Short, The 24-Hours dietary recall, and Bio-physiological measurements' tool. Results: There were significant post-intervention improvements in the total mean scores among study group regarding healthy dietary practices as it increased from 37.8±4.6 on pre-intervention to 49.6±5.8 post, body weight measures significantly decreased from 80.0±16.7 pre- to 73.4±18.3 post- and body mass index decreased from 30.1±12.2 pre- to 27.6±13.1 post. Besides, liver enzymes' total post-intervention mean scores for study group significantly reduced to 43.5±21.9 and 36.9±11.7 compared to control's 68.2±12.4 and 54.4±12.0, respectively for Aspartate aminotransferase and Alanine aminotransferase, likewise physical exercise practices' total post-intervention mean scores were statistically significant (p<0.05) . Conclusion: Lifestyle interventions; practicing of physical exercise and healthy nutrition, proved to be effective in gradual reduction of both bodyweight and liver-enzymes. Recommendations: Healthy lifestyle modifications should be considered as an initial step for both prevention and management of Non-alcoholic fatty-liver disease.

Keywords

International Egyptian Journal of Nursing Sciences and Research

Articles in Press, Accepted Manuscript
Available Online from 13 January 2024

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